Overview

Most suitable when

  • You need maximized throughput 
    The 8-channel system can produce a lot of data every day
  • You want to test and compare samples
    Running several samples at the same time lets you evaluate different parameters in one go
  • You need highly reproducible results
    The fully automated system minimizes the risk of user dependency and human error
  • You want to conduct experiments in both high and low temperatures
    The instrument works with a temperature range between 4-70 °C
  • You need more time
    The system can be pre-programmed and left unattended during experiments, leaving you with time to do other things 

3 reasons to invest

Increased productivity

The 8 channels of QSense Pro give you an opportunity to be fast and to produce lots of data every day. The fully automated system can be pre-programmed and left unattended during experiments, saving your time.

Compare several samples at the same time

Syringe pumps that run separately enable four channels to be used independently with different samples and measurement sequences. Hence, you can evaluate several parameter in parallel. 

Highly reproducible results

Automated measurements decrease the risk of user dependency and give you more reproducible results. Also, high precision flow-control is ensured by syringe pumps. Programming of automated mixing, including gradients of samples, increases reproducibility. 

Specifications

A closer look

Let's dive into the specifications of QSense Pro. 

Sensors and sample handling system

Number of sensors 8 (4 parallel in flow)
Volume above each sensor ~ 15 μl
Minimum sample volume ~ 50 μl
Working temperature ± 0.02 °C* 4 - 70 °C
Minimum dispense volume 1 μl**
Sensors Gold, SiO2, Ti and other metals, oxides, glass, polymers, etc.


Measurement characteristics

Maximum time resolution ~ 200 data points per second***
Maximum mass sensitivity in liquid ~ 0,5 ng/cm2****
Normal mass sensitivity in liquid ~ 1,8 ng/cm2*****
Maximum dissipation sensitivity in
liquid
~ 0.04 x 10-6****
Normal dissipation sensitivity in liquid ~ 0.1 x 10-6*****

Software

Analysis software QSense Dfind
Output parameters Frequency, dissipation, modeled values of mass, thickness and viscoelasticity
Import/export Excel, BMP, JPG, WMF, GIF, PCX, PNG, TXT


Dimensions

Instrument (HxWxL in cm) 70x57x67

* The temperature stability depends on variations in how the ambient temperature affects the warming or cooling of the chamber. ** Smallest sample volume to pick up and dispense. Note that the smallest volume
needed for measurement is 50 μl. *** One sensor, one frequency. Data from one sensor in single frequency mode. One data point collected every **** 5 seconds. The Sauerbrey relation is assumed to be valid.
***** Data from all sensors in multiple frequency modes (all harmonics) are collected within 1 second. The Sauerbrey relation is assumed to be valid. All specifications are subject to change without notice. 

Sensors

Sensors to match your needs

The choice of sensor is crucial for your experiment. To match your needs we have the widest range of quality sensors on the market, and we can customize both materials and coatings based on your wishes. 

Our sensors are developed and produced to provide you with stable, reliable and reproducible data. Full performance is ensured through extensive quality controls and guaranteed for one-time use according to the recommendations. Browse the list below to find your choice or contact us for a query on customized sensors.

Sensor description  Model system examples  Application examples
Aluminium (Al)  Electrodes  Electrochemistry, lithium insertion, energy
Aluminium Oxide (Al2O3) Water treatment plant, nanoparticles  Environmental
AlSiO  Kaolinite mimic  Energy, mining
Amine Coupling Biological, biochemical interactions  Antibody optimization, protein-protein interactions and probing of conformational changes
Amorphous Fluoropolymer AF1600 from DuPont Teflon, non-stick surfaces, inert surfaces  Protein surfaces, cleaning and detergent analysis, petroleum
Barium Titanate (BaTiO3)   Dielectric ceramic used for capacitors  
Biotin (on gold)  Biological, biochemical interaction  Molecular biology, protein interactions, antigens
Borosilicate glass  Labware, syringes, cookware  Pharmaceuticals, cleaning and detergent anlysis
Cellulose (on SiO2)  Fabric, filter, fiber  Enzyme interactions, cleaning and detergent analysis, electrochemistry, biofuels
Chromium (Cr)  Coating  Corrosion, electronics
Chromium Oxide (Cr2O3)  Used as pigment and occurs in nature as the mineral eskolaite  
Cobalt (Co)  Orthopedic implant, battery, pigment, porcelain  Medical device, energy, electroplating
Copper (Cu)  Wire, cables, coating  Corrosion, antifouling
Gold (Au)  Universal surface  Thiols, anything – everything sticks to gold
Gold (Au) without front electrode  Allows for own electrode material  
Gold (Ti Adhesion)  Universal surface  Fundamental electrochemistry
His-tag Capturing  Biological, biochemical interactions  Antibody studies, protein-protein, probing of conformational changes
Hydroxyapatite  Bone, teeth, bioinspired material, mineral  Biomaterials, medical device
Iron (Fe)  Combustion engine, nano particles  Corrosion, environmental transport, energy
Iron Oxide (Fe2O3)   Hematite mimic, nanoparticles, pipelines  Solar energy, photocatalyst, energy, environmental
Iron Oxide (Fe3O4) Magnetite mimic, pipelines, nanoparticles Pigment catalyst, corrosion, biofilm formation, environmental transport, energy
Indium Tin Oxide (ITO on Au) Solar panel Energy, solar cells
Magnesium (Mg) Mineral Energy, mining, also used in cars, bikes, cell phones
Molybdenum (Mo) Mineral Energy, mining (also replaces Tungsten in some applications and used as fertilizer)
Molybdenum disulphide (MoS2)  Mineral  Mining
NHS-Amine Coupling Biological, biochemical interaction Protein interactions, molecular biology, antigens
Nylon “6,6”  Nylon fabric Cleaning and detergent analysis
Palladium (Pd)  Catalyst  Catalysis
Polyethylenimine (PEI) Additive, flocculating agent  Detergents, adhesives, water treatment agents, cosmetics, wet-strength agent in the paper-making process.
Platinum (Pt) Electrodes Fuel cells, catalytic converters, energy
Polystyrene (PS) Hydrophobic surface, filters Cell studies, inert surfaces, filter interaction, medical device
Polymethyl Methacrylate (PMMA) Plexiglass, microfluidic material, biomaterial, bonecement, dentalfilling, lenses Biomedical, aquariums, car headlights
Polyvinylidene Fluoride(PVDF) Plastic, pharmaceutical filter and falcon tube Container interactions, harmaceutical industry
Silicon (Si) Semiconductor Energy, etching
Silicon Carbide (SiC) Rare mineral moissanite, carbone supporters, electrodes Energy, catalysts, electronics
Silicon Dioxide (SiO2) Glass Etching processes, silanization, cleaning and detergent analysis
Silicon Nitride (SiN) Biomaterials, integrated circuits Electronics, medical device
Silicon Oxycarbide (SiOC) Carbon supports, electrodes Catalysts, LEDs, brakes, graphene production, energy
Silver (Ag) Nano particles, antimicrobial coating Environmental transport, coatings, materials
Soda-lime glass Household glass (bottles, jars) labware Cleaning products, surface interactions
Stainless Steel (SS2343, US 316) Acid resistant steel Environmental, polluted industrial or city environments
Stainless Steel (L605) Stents Medical device, biomaterials, blood coagulation
Tantalum (Ta) Electrodes, reactors Alloys, electronics, energy
Tantalum Nitride (TaN) Electrodes Electronics
Titanium (Ti) Medical implants Medical device, biomaterials
Tungsten (W) Electrodes Etching processes
Zinc Oxide (ZnO) Minerals Mining, energy, rubber manufacture, ceramic industry, calamine lotion
Zinc Sulfide (ZnS)  Mineral Energy, mining, luminiscent and optical material, pigment
Zirconium Oxide (ZrO) Ceramics, fuel cell, membrane Alloys sintering, energy

Standardized soils*

   
Standardized used cooking oil    
Mixed starch, colored (CFT DM 77)  
Egg Yolk, double (CFT DM 22)  
Coffee with milk (CFT DM 83)  

Sensors come in packs of minimum 5. * Deposited on SiO2

Software

QSoft and Dfind software

QSense softwares are designed for you to make the most out of your QCM-D measurements. QSoft is collecting your data whereas Dfind makes your analysis easier.

Dfind features

  • A complete analysis toolbox 
    One software for all your needs 
  • Intuitive interface 
    Dfind supports you all the way through your analysis process - from data preparation to final reporting
  • Guided modelling
    To take you through your analysis step by step 
  • Material library
    Configuring your modelling setup is easy, just select your sample material from the list
  • Autoplotting
    Visualizes your results throughout the whole analysis
  • Smart tools
    Dfind offers several analysis methods including shifts, rates and slopes to help you extract the information you need
  • Analyze all data in one go
    To save your time, Dfind allows you to review, model and analyze multiple data sets in one go

Computer requirements

Required
  • PC with 64-bit Windows 7 SP1, 8, 8.1 or 10
  • At least 1366×768 px screen resolution
  • At least 4 GB RAM


Recommended
  • 1920×1080 Full HD screen resolution.
  • At least 8 GB RAM
  • At least 50 GB HD space
  • Core i5 5th generation Intel (or comparable) processor or better

Accessories

Add more possibilities

Have a look at selected add-ons compatible with QSense Pro. Please note that adding a chamber will take away the opportunity to run parallell samples, on the other hand, it can widen your experimental setting. 

Recommendations

What others say

Our instruments are present at many prestigious universities and research facilities world wide. Take a minute to find out what others say about QSense. 

citat8

Malkiat Johal on QSense

"I have found QSense to be one of the best techniques for an undergraduate lab because it’s turnkey and it requires very little maintenance."

Johal Malkiat-1

Malkiat Johal, Professor of Chemistry, Pomona College

"The operating principles are straightforward and the students can focus on the science. And so, that’s something that we have been really happy with, it really works in this kind of setting. It’s an ideal method for an undergraduate surface science lab."

citat8

Jodie Lutkenhaus on QSense

"We can monitor the mass change of our system in real-time. I can tell you that for every electron moved, this amount of mass changed. That’s powerful. You can’t really get that with any other system."

Jodie Lutkenhaus

Jodie Lutkenhaus, Associate Professor, Texas A&M University

"We use the QSense high temperature model that allows us to investigate polyelectrolyte complexes and their response to temperature. We’re also using the electrochemistry module so we can run our standard electrochemical measurements at the same time as we run the QCM-D."

citat8

Kenichi Sakai on QSense

"We regard QCM-D as a valuable measuring tool due to its high sensitivity and stability and find it applicable for versatile studies because of its availabilities of sensors with different types of surfaces. In this context I would say QCM-D is the best suitable solution for simulating a variety of nanoscale interaction behaviors both real-time & in-situ.

Jodie Lutkenhaus-1

Kenichi Sakai, Associate Professor, Tokyo University of Science

"We are working on academic research in the field of colloid and interface chemistry and our main work is synthesis of novel surfactants and characterization of their properties. We use QCM-D as a must-tool to comprehend molecular adsorption/desorption behaviors specifically observed at a solid-liquid interface."

citat8

Marité Cárdena on QSense

"QSense instruments are a great tool for our biophysical research. They enable rapid screening for biomolecular interaction at lipid bilayers and also allow optimising the parameters for deposition of thin films."

malm? universitet

Professor Dr. Marité Cárdenas, Health and Society, Malm? University

"The instrument is easy to use, and has a long working life as long as you follow the maintenance instructions! The technical staff at Biolin Scientific are a pleasure to work with: They are nice and always give quick feedback and support."

Knowledge

Learn more

We have gathered all our in-depth knowledge associated with QSense Pro. Browse around amongst guides, overviews and white papers to find a topic of interest. 

  • QSense
Guide

How to read a QCM Specification

There are key parameters to keep an eye on when investing in a new QCM instrument. Learn what they mean, and why they are important.

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  • QSense
Overview

Information Obtained with QSense QCM-D

We have summarized the parameters and processes that can be studied with QCM-D for you.

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  • QSense
Overview

How to Characterize Lipid-Based Systems with QCM-D

You get a brief overview of how to analyze lipid layer formation dynamics, structure and layer quality.

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  • QSense
Guide

QSense Cleaning Profile

Explore a new way to evaluate product performance of detergents with our step-by-step guide.

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  • QSense
White Paper

QCM-D vs other QCMs

We sort out the the differences between QCM methods to answer the question - does it matter which one I use?

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  • QSense
Overview

The Sauerbrey Relation

Time to learn how the Sauerbrey relation is derived and what the parameters mean.

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  • QSense
Guide

QCM-D Data Analysis

We put together guidelines for you on how to evaluate which method to use, and what happens if you choose the wrong approach.

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  • QSense
Overview

QCM-D Studies of Engineered Nanoparticles

In this overview we explore three examples of nanoparticle analysis with QCM-D.

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  • QSense
Overview

Analytical Methods to Characterize Lipid-based Systems

In this overview, Prof. Nam-Joon Cho, Nanyang Technological University, Singapore, has compiled a list of the analytical methods he uses in his research to characterize lipid-based systems.

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  • QSense
Video

Development of a New Method for the Formation of SLBs on Solid Support using QSense QCM-D

Watch our interview with Prof. Nam-Joon Cho, Nanyang Technological University, about the SALB-project.

Watch
  • QSense
Webinar

Determining Cleansing Efficacy of Elfan AT 84 using a QCM-D Assay

Hear Fredrik Andersson, Scientist at Global R&D, Nouryon, talk about how they used the QSense results to differentiate Elfan AT 84.

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  • QSense
Case Study

Analyzing Cleaning of Hard Surfaces with QSense

Learn how to assess cleaning efficiency using model and standardized stains.

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  • QSense
Guide

QSense Etching Guide

Learn how to use QSense technology for assessment of detergent etching properties.

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  • QSense
List

QCM-D in Research

Explore the work of Prof. Nam-Joon Cho and his research group through their publications.

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  • QSense
Overview

Key Publications on the Formation of Supported Lipid Bilayers

We gathered 8 research studies where QCM-D was used as a central analysis method.

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  • QSense
Overview

QCM-D vs SPR

Learn more about the differences between the two methods to find out which you should use.

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  • QSense
Overview

The Working Principles of QCM and QCM-D

Learn the fundamentals of how the technologies work, and what is the difference between them.

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  • QSense
Overview

What is Dissipation?

This is your chance to find out what it is, why it is important, and how it can be measured.

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  • QSense
Overview

Temperature Stability in QCM Measurements

Achieve reliable and reproducible QCM measurements by controlling the temperature.

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  • QSense
Guide

How to Generate Quality QCM-D Data

Follow our checklist for high-quality data and reproducible measurements.

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  • QSense
Overview

How QCM Results are Influenced by Layer Distribution

The distribution of the measured layer is key to your results. Discover why and how to handle it.

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  • QSense
Overview

What is Piezoelectricity?

Bone, wood and quartz are all piezoelectric materials. Learn about piezoelectricity and how it works

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  • QSense
Overview

QCM-D vs other QCMs

Let this brief overview guide you to your most suitable choice of QCM.

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  • QSense
Guide

How to Optimize the QCM-D Baseline Stability

9 steps to eliminate error sources and optimize reproducibility

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  • QSense
Overview

Characterization of Polymer-based Systems

Analyze layer build-up, conformation and molecular interaction with QSense QCM-D

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  • QSense
Case Study

QCM-D in Drug Formulation and Storage

Analyze and quantify protein adsorption to surfaces.

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  • QSense
Case Study

Analysis of Surfactant-Surface Interactions with QSense

Find out how to analyze surfactant interaction with surfaces at the nanoscale.

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  • QSense
Overview

What is Viscoelasticity?

Ice, wood and a disks in the human spine are all viscoelastic materials. What does it really mean?

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  • QSense
Overview

Characterization of Biomolecular Interactions

Learn how biomolecular interactions can be analyzed using QSense? QCM-D technology and what information you can get.

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  • QSense
Webinar

Dfind Basic Training Course

Learn the basics of Dfind, get a walk-through of the software and watch two live demo examples.

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  • QSense
Webinar

Basics of QCM-D

Learn the fundamentals of the technology, its possibilities and limitations and get a deeper understanding of nanometer layers.

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